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How Inversion Occurs During Gene Mutation

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How Inversion Occurs During Gene Mutation

Question

Explain how the inversion occurs during gene mutation.

Answer

During gene mutation, an inversion occurs when a segment of the DNA sequence is flipped in the opposite orientation - a DNA may break and during rejoining it is turned through an angle of 180°. As a result, the order of the nucleotides within the inverted segment is reversed.
The impact of an inversion during gene mutation on an organism depends on the specific genes involved and the extent of gene disruption caused by the inversion. In some cases, inversions may have no noticeable effect, while in others, they can lead to genetic disorders or diseases with significant implications for the individual's health and development.